Taddeucci A, Torre V, Rosenwasser N, Saccani P, Olivero G, Bruno S, Giunti D, Uccelli A, Usai C, Pittaluga A. 
Acute "in vivo" LPS causes an early presynaptic C1q and C3 accumulation and increases the "prunability" of cortical synaptosomes. 
Neurochem Int. 2026 Mar 4:106132. doi: 10.1016/j.neuint.2026.106132. 

Tessitore S, Torazza C, Bonifacino T, Bacchetti F, Roselli F, Raiteri L, Milanese M, Bonanno G.
Focus on the excitatory and inhibitory neurotransmission imbalance in amyotrophic lateral sclerosis: a harmful disease player or a potential therapeutic opportunity?
Neurobiol Dis. 2026 Feb;219:107272. doi: 10.1016/j.nbd.2026.107272. 

Rosso F, Magdalena R, Torazza C, Bacchetti F, Milanese M, Poletti A, Bonanno G, Cristofani R, Bonifacino T.
Non-cell autonomous autophagy in amyotrophic lateral sclerosis: A new promising target?
Neurobiol Dis. 2026 Jan;218:107203. doi: 10.1016/j.nbd.2025.107203. 

Benatti C, Roggeri A, Toscano Y, Torre V, Brunello N, Tascedda F, Blom JMC, Pittaluga A. 
Differences in presynaptic hippocampal GABAergic terminals at the early stage of life in female and male mice: effect of an acute early inflammatory challenge.
Neurochem Int. 2025 Nov;190:106062. doi: 10.1016/j.neuint.2025.106062.

Raiteri L, Cerminara M, Puliti A, Pittaluga A.
Glycine Release Is Upregulated by Metabotropic Glutamate Receptor 1 in Mouse Hippocampus.
Biomedicines. 2025 Dec 17;13(12):3106. doi: 10.3390/biomedicines13123106.

Pittaluga A, Torre V, Olivero G, Rosenwasser N, Taddeucci A.
Non-canonical Roles of Complement in the CNS: From Synaptic Organizer to Presynaptic Modulator of Glutamate Transmission.
Curr Neuropharmacol. 2025;23(7):820-834. doi: 10.2174/011570159X327960240823065729. 

Ciampi C, Fagiani F, Murtaj V, Comella F, Torre V, Filibian M, Andolfo A, Braccia C, Opallo N, Bottone MG, Pedrini E, Lucarini E, Bove M, Govoni S, Ghelardini C, Meli R, Trabace L, Pittaluga A, Mattace Raso G, Di Cesare Mannelli L, Lanni C. 
Intestinal inflammation induces glymphatic remodeling, priming early neurodegenerative signals in male mice. 
Alzheimers Dement. 2025 Oct;21(10):e70640. doi: 10.1002/alz.70640.

Torre V, Marchese E, Willison E, Monaco M, Bozzo M, De Negri Atanasio G, Taddeucci A, Trebesova H, Rispo F, Rosenwasser N, Turrini F, Olivero G, Candiani S, Grasselli E, Marchese A, Alcaro S, Boggia R, Romeo I, Grilli M, Di Pilato V, Costa G, Pittaluga A.
Presynaptic release-regulating α2 receptors and Urolithins: A bridge between systemic EA administration and central health properties.
Biomed Pharmacother. 2025 Jul;188:118187. doi: 10.1016/j.biopha.2025.118187.

Monaco M, Torazza C, Fedele E, Grilli M.
The impact of the exposome on Alzheimer's disease.
Int J Mol Sci. 2025 Mar 26;26(7):3015. doi: 10.3390/ijms26073015.

Schepers M, Vangansewinkel T, Libberecht K, Jeurissen H, Jacobs D, Piccart E, Prior R, Ricciarelli R, Brullo C, Fedele E, Bruno O, Prickaerts J, Lambrichts I, Van Den Bosch L, Vanmierlo T, Wolfs E.
Phosphodiesterase 4D inhibition improves the functional and molecular outcome in a mouse and human model of Charcot Marie Tooth disease 1 A.
Biomed Pharmacother. 2025 Feb;183:117828. doi: 10.1016/j.biopha.2025.117828.

Balbi M, Torazza C, Altosole T, Ravera S, Farinini E, Tessitore S, Bacchetti F, Rosso F, Musante I, Alfei S, Cerminara M, Puliti A, Filaci G, Fenoglio D, Leardi R, Fedele E, Bonanno G, Milanese M, Bonifacino T.
The complex phenotype and function of spinal cord microglia during ALS progression and the impact of metabotropic glutamate receptor type 5 down-regulation in SOD1G93A mice. 
Neurobiol Dis. 2025 Sep;213:107017. doi: 10.1016/j.nbd.2025.107017. 

Fioretti PV, Barbieri A, Migazzi A, Bressan D, Grassano M, Donini L, Roccuzzo M, Torrieri MC, Conci F, Ferracci E, Invernizzi S, Bowden KM, Bacchetti F, Cappelli S, Peroni D, Belli R, Pancher M, Mugoni V, Scarduelli G, Gianesello M, Pasetto L, Canarutto G, Carra S, Soldano A, Bisio A, Robbiati S, Valentini C, Nardella C, Piazza S, D'Agostino VG, Quattrone A, Sleiman S, Whitfield JR, Soucek L, Vignoli B, Viero G, Tiberi L, Zippo A, Demichelis F, Bonetto V, Buratti E, Verde F, Ticozzi N, Calvo A, Ratti A, Shaw PJ, Terenzio M, Chiacchiera F, Pennuto M, Basso M. 
MYC-driven gliosis impairs neuron-glia communication in amyotrophic lateral sclerosis. 
Brain. 2025 Sep 26:awaf360. doi: 10.1093/brain/awaf360.

Marini C, Riondato M, Dighero E, Democrito A, Losacco S, Emionite L, Nobbio L, Di Patrizi I, Camera M, Ghersi C, Ghelardoni M, Lanfranchi F, Vitale F, Carta S, Chiesa S, Torazza C, Milanese M, Bauckneht M, Hamedani M, Zaottini F, Schenone A, Martinoli C, Grillo F, Sambuceti G. 
Increased [18F]DPA-714 Uptake in the Skeletal Muscle of SOD1G93A Mice: A New Potential of Translocator Protein 18 kDa Imaging in Amyotrophic Lateral Sclerosis.
Biomolecules. 2025 May 31;15(6):799. doi: 10.3390/biom15060799.

Bonifacino T, Mingardi J, Torazza C, Popoli M, Bonanno G, Milanese M, Musazzi L.
Psychotropic drug-dependent modulation of excitatory-inhibitory balance in the prefrontal cortex of rats exposed to acute footshock stress.
Eur Neuropsychopharmacol. 2025 Aug;97:12-13. doi: 10.1016/j.euroneuro.2025.06.006. 

Souza INO, Balerio GN, Pandy V, Grilli M, Neves GA. 
World no-tobacco: effects of second-hand smoke (SHS) and vapors on the developing and adult brain. 
Front Pharmacol. 2025 May 6;16:1610178. doi: 10.3389/fphar.2025.1610178. 

Guidolin D, Tortorella C, Cervetto C, Marcoli M, Maura G, Agnati LF. 
Interaction Between Oxytocin and Dopamine Signaling: Focus on the Striatum. 
Int J Mol Sci. 2025 Sep 6;26(17):8711. doi: 10.3390/ijms26178711. 

Mapelli L, Di Domenico D, Sciacca G, Mainardi F, Ottaviani A, Monteverdi A, Tedesco M, Battaglia CR, Tritto S, Gandolfo M, Imfeld K, Kiderlen S, Krainer L, Cervetto C, Marcoli M, Sing A, Andersen J, Birey F, Sloan SA, Maccione A, D'Angelo E. 
Enhanced electrophysiological recordings in acute brain slices, spheroids, and organoids using 3D high-density multielectrode arrays. 
PLoS One. 2025 Sep 4;20(9):e0328903. doi: 10.1371/journal.pone.0328903. 

Farsetti E, Amato S, Averna M, Guidolin D, Pedrazzi M, Maura G, Agnati LF, Cervetto C, Marcoli M.
Dual Oxytocin Signals in Striatal Astrocytes.
Biomolecules. 2025 Aug 4;15(8):1122. doi: 10.3390/biom15081122.

Ravera S, Farsetti E, Maura G, Marcoli M, Bozzo M, Cervetto C, Amaroli A.
810-nm Photobiomodulation Evokes Glutamate Release in Normal and Rotenone-Dysfunctional Cortical Nerve Terminals by Modulating Mitochondrial Energy Metabolism.
Cells. 2025 Jan 7;14(2):67. doi: 10.3390/cells14020067.

Olivero G, Taddeucci A, Vallarino G, Trebesova H, Roggeri A, Gagliani MC, Cortese K, Grilli M, Pittaluga A.
Complement tunes glutamate release and supports synaptic impairments in an animal model of multiple sclerosis.
Br J Pharmacol. 2024 Jun;181(12):1812-1828. doi: 10.1111/bph.16328. 

Busceti CL, Di Menna L, Castaldi S, D’Errico G, Taddeucci A, Bruno V, Fornai F, Pittaluga A, Battaglia G, Nicoletti F.
Adaptive changes in group-II metabotropic glutamate receptors underlie the deficit in recognition memory induced by methamphetamine in mice.
eNeuro. 2024 Jul 5:ENEURO.0523-23.2024. doi: 10.1523/ENEURO.0523-23.2024.

Schepers M, Hendrix S, Mussen F, van Breedam E, Ponsaerts P, Lemmens S, Hellings N, Ricciarelli R, Fedele E, Bruno O, Brullo C, Prickaerts J, Van Broeckhoven J, Vanmierlo T.
Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition.
Neurotherapeutics. 2024 May 16;21(4):e00372. doi: 10.1016/j.neurot.2024.e00372.

Valenza M, Facchinetti R, Torazza C, Ciarla C, Bronzuoli MR, Balbi M, Bonanno G, Popoli M, Steardo L, Milanese M, Musazzi L, Bonifacino T, Scuderi C.
Molecular signatures of astrocytes and microglia maladaptive responses to acute stress are rescued by a single administration of ketamine in a rodent model of PTSD.
Transl Psychiatry. 2024 May 25;14(1):209. doi: 10.1038/s41398-024-02928-6.

Raffaele S, Nguyen N, Milanese M, Mannella FC, Boccazzi M, Frumento G, Bonanno G, Abbracchio MP, Bonifacino T, Fumagalli M.
Montelukast improves disease outcome in SOD1G93A female mice by counteracting oligodendrocyte dysfunction and aberrant glial reactivity
Br J Pharmacol. 2024 May 15. doi: 10.1111/bph.16408. O 

Alfei S, Zuccari G, Bacchetti F, Torazza C, Milanese M, Siciliano C, Athanassopoulos CM, Piatti G, Schito AM. 
Synthesized Bis-Triphenyl Phosphonium-Based Nano Vesicles Have Potent and Selective Antibacterial Effects on Several Clinically Relevant Superbugs.
Nanomaterials (Basel). 2024 Aug 15;14(16):1351. doi: 10.3390/nano14161351.

Bacchetti F, Schito AM, Milanese M, Castellaro S, Alfei S.
Anti Gram-Positive Bacteria Activity of Synthetic Quaternary Ammonium Lipid and Its Precursor Phosphonium Salt
Int J Mol Sci. 2024 Feb 27;25(5):2761. doi: 10.3390/ijms25052761. 

Trebesova H, Monaco M, Baldassari S, Ailuno G, Lancellotti E, Caviglioli G, Pittaluga AM, Grilli M. 
Unveiling Niaprazine's Potential: Behavioral Insights into a Re-Emerging Anxiolytic Agent.
Biomedicines. 2024 Sep 12;12(9):2087. doi: 10.3390/biomedicines12092087. 

Amato S, Averna M, Farsetti E, Guidolin D, Pedrazzi M, Gatta E, Candiani S, Maura G, Agnati LF, Cervetto C, Marcoli M.
Control of Dopamine Signal in High-Order Receptor Complex on Striatal Astrocytes.
Int J Mol Sci. 2024 Aug 7;25(16):8610. doi: 10.3390/ijms25168610. 

Parodi G, Zanini G, Collo L, Impollonia R, Cervetto C, Frega M, Chiappalone M, Martinoia S. 
In vitro electrophysiological drug testing on neuronal networks derived from human induced pluripotent stem cells. 
Stem Cell Res Ther. 2024 Nov 17;15(1):433. doi: 10.1186/s13287-024-04018-2.

Raiteri L.
Interactions Involving Glycine and Other Amino Acid Neurotransmitters: Focus on Transporter-Mediated Regulation of Release and Glycine–Glutamate Crosstalk
Biomedicines 2024, 12(7), 1518; https://doi.org/10.3390/biomedicines12071518

Olivero G, Grilli M, Marchi M, Pittaluga A.
Metamodulation of presynaptic NMDA receptors: New perspectives for pharmacological interventions.
Neuropharmacology. 2023 Aug 15;234:109570. doi: 10.1016/j.neuropharm.2023.109570. 

Roggeri A, Olivero G, Usai C, Vanmierlo T, Pittaluga A.
Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720.
Cells. 2023 Sep 24;12(19):2343. doi: 10.3390/cells12192343. 

Olivero G, Roggeri A,Pittaluga A. 
Anti-NMDA and Anti-AMPA Receptor Antibodies in Central Disorders: Preclinical Approaches to Assess Their Pathological Role and Translatability to Clinic. 
Int J Mol Sci. 2023 Oct 5;24(19):14905. doi: 10.3390/ijms241914905. 

Pittaluga A, Grilli M, Olivero G. 
Progress in metamodulation and receptor-receptor interaction: From physiology to pathology and therapy. 
Neuropharmacology. 2023 Oct 1;237:109639. doi: 10.1016/j.neuropharm.2023.109639. 

Paes D, Schepers M, Willems E, Rombaut B, Tiane A, Solomina Y, Tibbo A, Blair C, Kyurkchieva E, Baillie GS, Ricciarelli R, Brullo C, Fedele E, Bruno O, van den Hove D, Vanmierlo T, Prickaerts J. 
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology. 
Cell Mol Life Sci. 2023 Jun 12;80(7):178. doi: 10.1007/s00018-023-04804-w.

Fedele E.
Anti-Amyloid Therapies for Alzheimer’s Disease and the Amyloid Cascade Hypothesis.
Int J Mol Sci. 2023 Sep 24;24(19):14499. doi: 10.3390/ijms241914499.

Schepers M, Paes D, Tiane A, Rombaut B, Piccart E, van Veggel L, Gervois P, Wolfs E, Lambrichts I, Brullo C, Bruno O, Fedele E, Ricciarelli R, Ffrench-Constant C, Bechler ME, van Schaik P, Baron W, Lefevere E, Wasner K, Grünewald A, Verfaillie C, Baeten P, Broux B, Wieringa P, Hellings N, Prickaerts J, Vanmierlo T.
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
Brain Behav Immun. 2023 Mar;109:1-22. doi: 10.1016/j.bbi.2022.12.020.

Mingardi J, Ndoj E, Bonifacino T, Misztak P, Bertoli M, La Via L, Torazza C, Russo I, Milanese M, Bonanno G, Popoli M, Barbon A, Musazzi L.
Functional and Molecular Changes in the Prefrontal Cortex of the Chronic Mild Stress Rat Model of Depression and Modulation by Acute Ketamine.
Int J Mol Sci. 2023 Jun 28;24(13):10814. doi: 10.3390/ijms241310814.

Bonifacino T, Mingardi J, Facchinetti R, Sala N, Frumento G, Ndoj E, Valenza M, Paoli C, Ieraci A, Torazza C, Balbi M, Guerinoni M, Muhammad N, Russo I, Milanese M, Scuderi C, Barbon A, Steardo L, Bonanno G, Popoli M, Musazzi L.
Changes at glutamate tripartite synapses in the prefrontal cortex of a new animal model of resilience/vulnerability to acute stress.
Transl Psychiatry. 2023 Feb 18;13(1):62. doi: 10.1038/s41398-023-02366-w.

Torazza C, Provenzano F, Gallia E, Cerminara M, Balbi M, Bonifacino T, Tessitore S, Ravera S, Usai C, Musante I, Puliti A, Van Den Bosch L, Jafar-Nejad P, Rigo F, Milanese M*,Bonanno G.
Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes.
Cells. 2023 Jul 27;12(15):1952. doi: 10.3390/cells12151952.

Forti L, Ndoj E, Mingardi J, Secchi E, Bonifacino T, Schiavon E, Carini G, La Via L, Russo I, Milanese M, Gennarelli M, Bonanno G, Popoli M, Barbon A, Musazzi L.
Dopamine-Dependent Ketamine Modulation of Glutamatergic Synaptic Plasticity in the Prelimbic Cortex of Adult Rats Exposed to Acute Stress.
Int J Mol Sci. 2023 May 13;24(10):8718. doi: 10.3390/ijms24108718.

Cervetto C, Pistollato F, Amato S, Mendoza-de Gyves E, Bal-Price A, Maura G, Marcoli M.
Assessment of neurotransmitter release in human iPSC-derived neuronal/glial cells: a missing in vitro assay for regulatory developmental neurotoxicity testing.
Reprod Toxicol. 2023 Apr;117:108358. doi: 10.1016/j.reprotox.2023.108358. Epub 2023 Mar 1.

Amato S, Averna M, Guidolin D, Ceccoli C, Gatta E, Candiani S, Pedrazzi M, Capraro M, Maura G, Agnati LF, Cervetto C, Marcoli M.
Heteromerization of Dopamine D2 and Oxytocin Receptor in Adult Striatal Astrocytes.
Int J Mol Sci. 2023 Feb 28;24(5):4677. doi: 10.3390/ijms24054677.

Taddeucci A, Olivero G, Roggeri A, Milanese C, Giorgio FPD, Grilli M, Marchi M, Garrone B, Pittaluga A.
Presynaptic 5-HT_2A-mGlu2/3 Receptor-Receptor Crosstalk in the Prefrontal Cortex: Metamodulation of Glutamate Exocytosis.
Cells. 2022 Sep 28;11(19):3035. doi: 10.3390/cells11193035. 

Iovino L, Giusti V, Pischedda F, Giusto E, Plotegher N, Marte A, Battisti I, Di Iacovo A, Marku A, Piccoli G, Bandopadhyay R, Perego C, Bonifacino T, Bonanno G, Roseti C, Bossi E, Arrigoni G, Bubacco L, Greggio E, Hilfiker S, Civiero L.
Trafficking of the glutamate transporter is impaired in LRRK2-related Parkinson’s disease.
Acta Neuropathol. 2022 Jul;144(1):81-106. doi: 10.1007/s00401-022-02437-0.

Bonifacino T, Micheli L, Torazza C, Ghelardini C, Farina C, Bonanno G, Milanese M, Di Cesare Mannelli L, Scherz MW.
Pharmacological Profile of MP-101, a Novel Non-racemic Mixture of R- and S-dimiracetam with Increased Potency in Rat Models of Cognition, Depression and Neuropathic Pain.
Cells. 2022 Dec 13;11(24):4027. doi: 10.3390/cells11244027.

Amato S, Averna M, Guidolin D, Pedrazzi M, Pelassa S, Capraro M, Passalacqua M, Bozzo M, Gatta E, Anderlini D, Maura G, Agnati LF, Cervetto C, Marcoli M.
Heterodimer of A2A and Oxytocin Receptors Regulating Glutamate Release in Adult Striatal Astrocytes.
Int J Mol Sci. 2022 Feb 19;23(4):2326. doi: 10.3390/ijms23042326. 

Marcoli M, Cervetto C, Amato S, Fiorucci C, Maura G, Mariottini P, Cervelli M.
Transgenic Mouse Overexpressing Spermine Oxidase in Cerebrocortical Neurons: Astrocyte Dysfunction and Susceptibility to Epileptic Seizures.
Biomolecules. 2022 Jan 25;12(2):204. doi: 10.3390/biom12020204.

Villa V, Montalto G, Caudano F, Fedele E, Ricciarelli R.
Selective inhibition of phosphodiesterase 4D increases tau phosphorylation at Ser214 residue.
Biofactors. 2022 Sep;48(5):1111-1117. doi: 10.1002/biof.1847.

Sala N, Paoli C, Bonifacino T, Mingardi J, Schiavon E, La Via L,  Milanese M , Tornese P, Datusalia AK, Rosa J, Facchinetti R, Frumento G, Carini G, Salerno Scarzella F, Scuderi C, Forti L, Barbon A, Bonanno G, Popoli M, Musazzi L.
Acute Ketamine Facilitates Fear Memory Extinction in a Rat Model of PTSD Along With Restoring Glutamatergic Alterations and Dendritic Atrophy in the Prefrontal Cortex.
Front Pharmacol. 2022 Mar 17;13:759626. doi: 10.3389/fphar.2022.759626. eCollection 2022.

Provenzano F, Nyberg S, Giunti D, Torazza C, Parodi B, Bonifacino T, Usai C, Kerlero de Rosbo N, Milanese M*, Uccelli A, Shaw PJ, Ferraiuolo L, Bonanno G.
Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS.
Cells. 2022 Dec 4;11(23):3923. doi: 10.3390/cells11233923. 

Fagiani F, Baronchelli E, Pittaluga A, Pedrini E, Scacchi C, Govoni S, Lanni C.
The Circadian Molecular Machinery in CNS Cells: A Fine Tuner of Neuronal and Glial Activity With Space/Time Resolution.
Front Mol Neurosci. 2022 Jul 1;15:937174. doi: 10.3389/fnmol.2022.937174.